Diagnosis of autoimmune hepatitis

ObjectiveTo enhance the understanding of the clinical features,diagnosis,treatment and prognosis of autoimmune hepatitis(AIH) and decrease AIH misdiagnosis.Methods twenty-six cases of AIH in Ma'anshan Hospital of Infectious Diseases and Rijin hospital were analyzed retrospectively.Results The majority of patients were women and the average age was(42.3±11.1) years.Thirty-two patients(84.61%) had insidous or chronic onset while five patients(19.23%) had acute onset.Nineteen patients(74.3%) showed unspecific manifestations of gastrointestinal tract,which made them go to to see a doctor.All of the patients had higher levels of aspartate aminotransferas(AST) and alanine aminotransferase(ALT).Twenty patients(76.92%) had higher level of bilirubin,and twenty-one(80.76%) had higher level of immunoglobulin.Twenty-two patients(83.25%) were positive for AIH-related antibodies.Conclusion AIH is usually misdiagnosed and its manifestations have no specificity.Early diagnosis and treatment will improve prognosis.

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